The concept of vagotomy (trunk, selective, selective proximal) and drainage operations on the stomach


Vagotomy technique

There are a large number of different modifications for performing both vagotomy and pyloroplasty. Vagotomy is distinguished between trunk subdiaphragmatic (intersection of the entire nerve in the thickness of the esophageal wall at the point where it exits through the diaphragm into the abdominal cavity), selective - intersection of branches that innervate only the stomach, and selective proximal - intersection of the trunks of the vagus nerve going to the upper parts of the stomach. Laparoscopically, vagotomy is more often performed, since pyloroplasty requires the use of expensive consumables (stitching devices, atraumatic suture material). Four to five trocars are used to perform vagotomy. Through one, a laparoscope is inserted, into three or four others - instruments for retracting and holding organs, as well as crossing the vagus nerve, which is carried out using endoscissors using coagulation. Often during the operation, endoscopic staplers or manual suturing of the stomach wall are used. Trocar wounds of 1 cm are sutured, 0.5 cm are sealed with a plaster. The operation is performed under anesthesia.

Stomach surgery

Stomach surgery ¦ Organ-preserving operations for gastric and duodenal ulcers

In case of gastric ulcer and/or duodenal ulcer, both complicated and uncomplicated, in accordance with the available indications, patients undergo organ-preserving surgical interventions - intersection of the branches of the vagus nerve, or vagotomy, the choice of method is carried out strictly on an individual basis.

The first subphrenic 2-sided truncal vagotomy was performed in 1932 by Piri. However, it should be noted that the method he proposed has significant drawbacks, because performing such an operation leads to parasympathetic denervation of the abdominal organs and disruption of their normal functioning: the appearance of atony of the stomach and gallbladder, the development of diarrhea, alkaline reflux gastritis, etc. Therefore, at the present stage, many experts believe that truncal vagotomy should be resorted to only in special cases.

The so-called “selective” gastric vagotomy, which consists in crossing only the anterior and posterior branches of the vagus going to the stomach below the place where the branches to the gallbladder and liver depart from it, is also fraught with certain complications and, in particular, causes problems with the pylorus, which requires drainage surgery, namely, pyloroplasty according to Heineke-Mikulich or Judd with excision of the ulcerative defect of the anterior wall of the stomach and part of the pylorus, or intervention according to Finney, or the creation of a bypass gastroduodenoanastomosis according to Dzhabula. However, such a step cannot in any way be called an organ-preserving element.

Most doctors with sufficient experience in performing vagotomy believe that the main organ-preserving operation for peptic ulcer disease should be proximal selective vagotomy, not accompanied by drainage intervention. This tactic was developed in 1964 by Holle and Hart; its essence consists of parasympathetic denervation of only the acid-producing zone, i.e. the body of the stomach and its fundus while maintaining the innervation of the pylorus and antrum. This method allows you to achieve an adequate reduction in gastric secretion and prevents the occurrence of dumping syndrome, alkaline reflux gastritis and diarrhea.

At the present stage, in order to reduce the morbidity of this operation, specialists use laparoscopic techniques to perform it. The entire procedure is carried out through four miniature puncture incisions on the anterior abdominal wall. Using special endoscopic instruments, the surgeon carefully isolates the posterior vagus nerve near the gastroesophageal junction and crosses it and its smaller branches with an ultrasonic dissector. The anterior branches of the vagus cross at the anterior wall of the lesser curvature of the stomach, moving from the esophagus to the angle of the stomach. To monitor the effectiveness of the intervention, a study is carried out with a special probe – pH meter. If a patient has a combined pathology: chronic calculous cholecystitis, hiatal hernia, it can also be corrected in parallel by performing laparoscopic cholecystectomy or laparoscopic Nissen or Toupet fundoplication.

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Postoperative complications with vagotomy

Possible complications during surgery include damage to the esophagus, bleeding from the gastric arteries. After vagotomies, recurrent ulcers occur quite often (up to 10%). Dumping syndrome (rapid evacuation of food from the stomach into the intestines and the associated complex symptom complex - weakness, sweating, palpitations, digestive disorders that occur after eating), duodeno-gastric reflux (reverse reflux of duodenal contents into the stomach - pain, regurgitation and vomiting of bile, constant bitterness in the mouth, weight loss), diarrhea (stool disorders). See also Complications possible after laparoscopy

Evolution of treatment for patients with GERD: from vagotomy to proven pharmacotherapy

GERD is called a disease of modern civilization or a diagnosis of the “Western lifestyle.” In addition to heartburn, its manifestations include belching and difficulty swallowing (dysphagia), which can cause serious discomfort to a person, reduce his quality of life, and the chronic course of the disease in some cases can lead to complications such as damage to the mucous membrane (esophagitis) and cancer ( adenocarcinoma) of the esophagus2. The prevalence of GERD among adults worldwide reaches 40%, and in Russia it affects from 18% to 46% of the adult population, and the incidence rate is growing1.

GERD develops as a result of regular reflux of stomach contents into the esophagus and is an acid-dependent disease, which also includes ulcers, etc. The treatment of such diseases has a long history: the first attempts to treat GERD were examples of alternative medicine and herbal medicine. In the 19th century, an “advanced” method was invented - vagotomy: it was proposed to treat severe heartburn and ulcers by cutting the nerve going to the stomach to “turn off” the secretion of hydrochloric acid. As a result, rehabilitation after surgery took many months, and the consequences of such an operation accompanied patients throughout their lives.3

A major breakthrough in therapy occurred in 1989, when a group of Swedish researchers led by Ivan Estholm invented the first proton pump inhibitor4, a molecule that can reduce the production of hydrochloric acid without surgery. This event played a key role in the development of a new approach to the treatment of GERD and marked a breakthrough in the treatment of digestive diseases. In 1993, at the International Congress of Gastroenterologists at Yale, it was decided to abandon vagotomy forever. In 2000, the next generation of PPIs, esomeprazole, was developed and launched on the market, which has been successfully used for the treatment of GERD, gastric and duodenal ulcers in 125 countries around the world for 20 years.4

  1. Ivashkin V.T., Maev V.I., Trukhmanov A.S. et al. Clinical guidelines of the Russian Gastroenterological Association for the diagnosis and treatment of gastroesophageal reflux disease. RZHGGK. 2017;27(4):75-95
  2. R. Jones, O. Junghard, J. Dent et al. Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther. 2009 Nov 15;30(10):1030-8
  3. Ivashkin V.T. School of clinician. Peptic ulcer disease - history of medicine. // Medical Bulletin. - 2006. - No. 19 (362). - p. 9-10.
  4. Olbe L., Carlsson E., Lindberg P. A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole. Nat Rev Drug Dis 2003; 2:132-9.

Postoperative regimen and rehabilitation.

On the first day until the evening, due to anesthesia, bed rest is prescribed, in the evening you can drink liquids, turn and sit up in bed, the next day you can get up and walk, take semi-liquid food. All dietary restrictions are lifted after a week. When pyloroplasty is performed simultaneously with vagotomy, the diet is prescribed for a period of up to 2-3 weeks.

During the first two weeks after surgery, wash in the shower; after washing, treat wounds with iodine solution or 5% potassium permanganate solution. Removal of sutures is usually not required. The usual mode of labor and physical work is possible after 3 weeks. See also Postoperative regimen and rehabilitation.

Advantages

The laparoscopic option for performing the intervention is obvious: significantly less trauma, excellent cosmetic effect, virtually no postoperative pain, shorter hospital stay, faster rehabilitation.

To the disadvantages

It can be attributed to the fact that the operation is performed, on average, a little longer (10-20 minutes) than with the open version and requires consumables. For more information, see 18 advantages and 4 disadvantages of laparoscopy.

Gastrointestinal surgery

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Anesthesiology and resuscitation

Service codeInternal codeNamePrice, rub
B01.003.004.00737.1.1Spinal anesthesia lasting up to 1 hour8 000
B01.003.004.00637.1.2Epidural anesthesia lasting up to 1 hour14 000
B01.003.004.00837.1.3Spinoepidural anesthesia lasting up to 1 hour20 000
B01.003.004.00937.1.4Total intravenous anesthesia up to 20 minutes6 000
B01.003.004.00937.1.5Total intravenous anesthesia from 20 minutes to 60 minutes12 000
B01.003.004.01037.1.6Endotracheal anesthesia from 1 hour to 2 hours20 000
B01.003.004.01037.1.7Endotracheal anesthesia from 2 hours to 3 hours26 000
B01.003.004.01037.1.8Endotracheal anesthesia from 3 hours to 4 hours34 000
B01.003.004.01037.1.9Endotracheal anesthesia from 5 to 6 hours58 000
B03.016.01137.1.10Express analysis of blood gases and electrolytes2 000
B03.016.01137.1.11Advanced express analysis of blood gases and electrolytes2 500
B03.016.01137.1.12Artificial ventilation for 12 hours7 200
B01.003.004.01037.1.13Endotracheal anesthesia up to 1 hour14 000
B01.003.004.01037.1.14Endotracheal anesthesia from 4 to 5 hours40 000
B01.003.004.00237.1.15Conduction anesthesia of the 1st category of complexity4 000
B01.003.004.00537.1.16Infiltration anesthesia (large volume or area) up to 30 minutes3 000
B01.003.004.00537.1.17Infiltration anesthesia up to 15 minutes1 400
B01.003.004.00437.1.18Application anesthesia1 000
B01.003.004.00937.1.19Drug sedation with hemodynamic monitoring3 000
B01.003.00437.1.20Prolonged regional anesthesia (days)8 000
A11.12.00137.1.21central vein catheterization10 000
A11.23.00237.1.22TAP TEST12 500
B01.003.004.00737.1.1.2Spinal anesthesia from 1 hour to 2 hours14 000
B01.003.004.00737.1.1.3Spinal anesthesia from 2 hours to 3 hours17 000
B01.003.004.00737.1.1.4Spinal anesthesia from 3 hours to 4 hours20 000
A11.23.003.00137.1.2.1Placement of an epidural catheter8 000
B01.003.004.00637.1.2.2Epidural anesthesia from 1 hour to 2 hours17 000
B01.003.004.00637.1.2.3Epidural anesthesia from 2 hours to 3 hours21 000
B01.003.004.00637.1.2.4Epidural anesthesia from 3 hours to 4 hours24 000
B01.003.004.00637.1.2.5Epidural anesthesia from 4 hours to 5 hours28 000
B01.003.004.00837.1.3.1Spinoepidural anesthesia from 1 hour to 2 hours22 000
B01.003.004.00837.1.3.2Spinoepidural anesthesia from 2 hours to 3 hours26 000
B01.003.004.00837.1.3.3Spinoepidural anesthesia from 3 hours to 4 hours27 000
B01.003.004.00837.1.3.4Spinoepidural anesthesia from 4 hours to 5 hours30 000
B01.003.004.00937.1.5.1Total intravenous anesthesia from 1 hour to 2 hours20 000
B01.003.004.00937.1.5.2Total intravenous anesthesia from 2 hours to 3 hours24 000
B01.003.004.01037.1.9.1Endotracheal anesthesia from 6 to 7 hours65 000
B01.003.004.01037.1.9.2Endotracheal anesthesia from 7 to 8 hours70 000
B01.003.004.00237.1.15.1Conduction anesthesia of the 2nd category of complexity5 000
B01.003.004.00237.1.15.2Conduction anesthesia of the 3rd category of complexity6 000

Hernia of the anterior abdominal wall (Tyumin A. A.)

Service codeInternal codeNamePrice, rub
A16.30.00137.46.1.1Open surgical treatment of inguinofemoral hernia90 000
A16.30.00237.46.10.1Surgical treatment of umbilical hernia, category 280 000
A16.30.001.00137.46.2.1Laparoscopic surgical treatment of inguinofemoral hernia110 000
A16.30.00237.46.4.1Surgical treatment of category 2 ventral hernia110 000
A16.30.00237.46.9.1Surgical treatment of category 1 umbilical hernia60 000

Gastrointestinal tract

Service codeInternal codeNamePrice, rub
A16.16.01037.39.1Gastrotomy25 000
A16.16.01037.39.2Gastrotomy, stitching of a bleeding stomach ulcer66 000
A16.16.01037.39.3Gastrotomy, suturing of gastric varicose veins100 000
A16.16.01537.39.4Gastrectomy (including transthoracic)180 000
A16.16.017.00437.39.5Proximal gastrectomy170 000
A16.16.017.00237.39.6Reconstructive gastrectomy190 000
A16.16.017.00137.39.7Distal gastrectomy145 000
A16.16.017.00837.39.8Segmental endoscopic gastrectomy200 000
A16.16.01137.39.9Pyloroplasty65 000
A16.16.02037.39.10Gastroenterostomy90 000
A16.16.02137.39.11Suturing of a perforated gastric or duodenal ulcer75 000
A16.16.021.00137.39.12Laparoscopic suturing of a gastric or duodenal ulcer110 000
A16.16.04737.39.13Installation of an endogastric balloon (without balloon cost)30 000
A16.16.04737.39.14Installation of the LAP-BAND system (without the cost of a gastric band160 000
A16.16.00437.39.15Cardiodilation of the esophagus50 000
A16.16.03337.39.16Fundoplication85 000
A16.16.033.00137.39.17Laparoscopic fundoplication130 000
A16.16.03437.39.18Gastrostomy55 000
A16.16.034.00137.39.19Laparoscopic gastrostomy70 000
A16.16.03637.39.20Reconstruction of gastroenteroanastomosis160 000
A16.17.00137.39.21Excision of small intestinal diverticulum50 000
A16.17.00537.39.22Small bowel resection60 000
A16.30.00637.39.23Laparotomy, dissection of adhesions in case of obstruction85 000
A16.30.00637.39.24Laparotomy for strangulated hernias with resection of a section of the small intestine with nasointestinal drainage140 000
A16.17.00737.39.25Ileostomy48 000
A16.17.00937.39.26Release of the small intestine from intussusception37 000
A16.17.01037.39.27Enetrotomy, removal of a foreign body50 000
A16.18.00437.39.28Total colectomy250 000
A16.18.01537.39.29Left hemicolectomy180 000
A16.18.01637.39.30Right hemicolectomy180 000
A16.18.017.00337.39.31Laparoscopic hemicolectomy250 000
A16.19.01937.39.32Resection of the sigmoid colon120 000
A16.19.021.00537.39.33Low anterior rectal resection250 000
A16.19.021.01037.39.34Anterior rectal resection170 000
A16.19.020.00337.39.35abdominoperineal extirpation of the rectum250 000
A16.18.00737.39.36Colostomy40 000
A16.18.00937.39.37Open appendectomy 1 stage50 000
A16.18.00937.39.38Open appendectomy 2nd stage70 000
A16.18.00937.39.39Open appendectomy 3rd stage110 000
A16.18.009.00137.39.40Laparoscopic appendectomy 1st stage60 000
A16.18.009.00137.39.41Laparoscopic appendectomy category 280 000
A16.18.009.00137.39.42Laparoscopic appendectomy category 3115 000
A16.17.01037.39.43Colotomy, foreign body removal50 000
A16.18.01237.39.44Formation of intestinal bypass anastomosis 1st stage55 000
A16.18.01237.39.45Formation of intestinal bypass anastomosis 2nd stage80 000
A16.19.02637.39.46Reconstructive surgery on the colon150 000
A16.19.021.01537.39.47transanal full-wall tumor excision150 000
A16.18.028.00137.39.48Laparoscopic removal of colonic fat pad50 000
A16.16.034.00337.39.49Percutaneous endoscopic gastrostomy (excluding cost of gastrostomy kit)30 000

General hospital services

Service codeInternal codeNamePrice, rub
S01.001.00137.0.1Stay in a hospital ward (daily)6 000
S01.001.00237.0.2Stay in a hospital ward (daytime until 21:00)3 000
S01.001.00337.0.3Stay in the ward for accompanying persons (daily)6 000
S01.001.00437.0.4Stay in hospital room VIP 1 (daily)10 000
S01.001.00537.0.5Stay in hospital room VIP 2 (daily)16 000
S01.001.00637.0.6Stay in a hospital ward (daily, without meals)3 400
S01.001.00737.0.7Stay in the intensive care unit from 6-24 hours8 000
B01.047.00937.0.9Supervision by a therapeutic physician (1 visit)2 500
A11.12.00337.0.10Infusion therapy of expensive drugs4 000
A23.01.00137.0.11Extraction of surgical material using delivery means (calculated price)1 000
A18.05.01337.0.22Treatment using blood products (calculation, price)1 000
A11.12.00337.0.23Treatment using additional drug therapy (calculation, price)1 000
A23.01.00137.0.24Selection of implants (calculation, price)1 000
S01.002.00137.0.25Selection of compression garments (calculation, price)1 000
B01.057.00137.0.28Appointment with an operating specialist0
A11.01.01437.0.29Hemostasis using local hemostatic agent Zhelplastan 2.5 g6 600
A11.01.01437.0.30Hemostasis using local hemostatic agent Zhelplastan 5.0 g12 700
A11.12.003.00237.0.31IV drip infusion of Ferinject 500 mg (Ferinject, 50 mg/ml, 2 ml No. 5 in ampoules or 50 mg/ml, 10 ml in a bottle), duration up to 30 minutes8 000
А11.12.003.00337.0.32IV drip infusion of Ferinject 1000 mg (Ferinject, 50 mg/ml, 10 ml in bottle No. 2), duration up to 30 minutes15 000
S01.001.00837.0.1.1Stay in a hospital room (overnight)3 000
S01.001.00937.0.4.1Stay in hospital room VIP 1 (no more than 12 hours)5 000
S01.001.01037.0.5.1Stay in hospital room VIP 2 (no more than 12 hours)8 000
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