GastrituNet.ru » Medicines » Proton pump inhibitors » Omeprazole
To treat gastrointestinal diseases, drugs from different pharmacological groups are used. Some medications are similar in their mechanism of action or are analogues of more expensive or unavailable medications. Therefore, the doctor sometimes has to choose which drug to prescribe - for example, Omeprazole or Omez.
Let's find out what is better than Omez or Omeprazole, what is the difference between them and whether they are interchangeable drugs.
So: Omez or Omeprazole – which is better, the opinion of experts in the field of pharmacology.
- 1 Brief information about Omez
- 2 Omeprazole
- 3 Comparison of drugs
- 4 Summing up
"Omez" and "Omeprazole" - what is it?
The purpose of these drugs is to suppress the production of hydrochloric acid by the gastric glands. Why is this suppression necessary? Hydrochloric acid is quite aggressive. When there is a history of gastritis or gastric ulcers, the acid will irritate unhealed wounds on the mucous membrane. If its production is suspended for a while, the shell will have every chance of recovery. Such treatment became possible with the study of proton pump inhibitor drugs, which include Omez or Omeprazole. This article will help you figure out which is better. We will also briefly describe the indications and contraindications, the differences between the drugs.
How they work
When it enters the gastrointestinal tract, the active ingredient begins to affect the functioning of gastric receptors 1-2 hours after administration. A single dose of Omez or Omeprazole for gastritis or ulcers is enough to create comfortable conditions for the gastrointestinal tract and provide a favorable environment in the stomach. Interacting with the acid-base environment, omeprazole, which is part of Omez and Omeprazole, inhibits and blocks the production of basal secretion, while acting on acetylcholine and histamine receptors.
Omez capsules and Omeprazole tablets - what for?
Unfortunately, gastritis and stomach ulcers have become commonplace. The causes of these diseases are hidden both in the unbalanced diet now and in the remnants of the “Union” nutrition standards, when children from one to three months were introduced to complementary foods with juices and cereals completely inappropriate for their age. Then the children’s stomachs coped with the overwhelming load, but nothing just goes away. We have a whole generation with gastritis of various etiologies.
The demand for drugs used to treat these diseases is high, but the supply is not inferior to it.
“Omez” or “Omeprazole” – which is better is difficult to answer, because these are two related drugs intended for the treatment of inflammatory processes of the gastrointestinal tract. They have common indications for use, and side effects are very similar. These are medicines with one active ingredient, but a significant difference in the availability of auxiliary agents.
Comparison of drugs
In order to be as objective as possible and find out which is better - Omez or Omeprazole, we will compare medications according to pharmacological and economic parameters.
Price
Omez is an Indian-made drug that costs about 200 rubles on average.
Generic Omeprazole is produced by foreign and domestic manufacturers.
The cheapest medicine is produced in Russia and costs about 40 rubles.
The average cost of imported Omeprazole is 130 rubles.
Quality
Despite the obvious price advantage of the domestic product, you should not chase savings - it is better to give preference to Omeprazole in the middle price category. After all, the quality of the drug substance depends on the cost - drugs with a higher price have better purification and less impact on the liver.
Indications and contraindications for use
It is precisely because of poor purification that inexpensive Omeprazole is contraindicated for liver diseases, while the instructions for Omez do not contain such a restriction on taking the medicine - use is permitted with caution on the recommendation of a doctor.
A cheap analogue of Omez is contraindicated for children, nursing and pregnant women, while the original drug is allowed to be used in pediatrics (in patients weighing more than 20 kg), nursing women and expectant mothers (with the permission of a doctor). Clinical studies have not revealed any negative effects on the health of the mother and offspring. By the way, Omeprazole has not undergone clinical trials at all.
Indications for use are also somewhat different - the list of gastroenterological pathologies for which Omez is effective is wider than that of Omeprazole.
Range of dosage forms
Here Omez has an advantage, whose product range includes powders for children and people with difficulty swallowing, capsules for oral administration and an injection solution.
Omeprazole is produced only in tablets.
Availability in pharmacies
Both products can be freely purchased at any pharmacy - there will be no problems finding them.
Side effects and tolerability
The most common side effects are dyspeptic symptoms and allergic reactions.
The severe consequences of taking medications are similar for both drugs. Most often this is a violation of mineral metabolism and osteoporosis.
"Omeprazole"
This is a drug that, by its action, interferes with the metabolic process and regulates the production of hydrochloric acid. The active ingredient is omeprazole in an amount of 20 mg.
Indications for use:
- stomach ulcers;
- duodenal ulcer;
- peptic ulcers;
- gastritis with normal and high acidity;
- Zollinger-Ellison syndrome (ulcer combined with benign neoplasms of the pancreas).
Active substances
The identical active substances that make up Omez and Omeprazole determine the therapeutic similarity of these drugs. The common component is omeprazole, which belongs to the group of proton pump inhibitors. Once in the acidic environment of the stomach, this ingredient affects the mucous membranes of the stomach.
Accumulating in the body, omeprazole reduces the production of hydrochloric acid - the main culprit of increased stomach acidity. Therefore, if you replace Omez (an analogue of Omeprazole) with another drug of similar composition, the restorative effect will be obvious: with a decrease in acidity, the walls of the digestive tract have a chance to recover and heal. The presence of omeprazole in medications as the main active ingredient reduces the risk of gastric bleeding.
"Omez." Briefly about the drug
"Omez" is a drug that affects the functioning of the proton pump. Active ingredient: omeprazole, 20 mg per capsule plus excipients. The components of the medicine are contained in granules that are resistant to acids. That is, the drug dissolves and begins to act in the intestines, and not in the stomach, which enhances its effect. The drug is used in the cases described above. But, in addition to the mentioned effects, taking Omez also significantly reduces stomach acidity and relieves heartburn. The drug is effective for about 24 hours; in uncomplicated cases, taking one capsule per day is sufficient. The drug is effective in the fight against Helicobacter bacteria. The drug is contraindicated during pregnancy and lactation; with some exceptions, treatment of children under 12 years of age is unacceptable.
Dosages
The treatment regimen according to which Omez or Omeprazole should be taken for gastritis or ulcers is identical:
- For manifestations of inflammatory processes in the gastrointestinal tract in the form of gastritis, accompanied by pain and increased secretion of gastric juice, gastric ulcers, the recommended dose of any of these drugs is 20 mg per day;
- In case of manifestations of Zollinger-Ellison syndrome, caused by the formation of a gastroproducing tumor, accompanied by hypersecretion of hydrochloric acid in the stomach, the dose of the active substance should be increased to 60-120 mg;
- In treatment regimens for influencing the manifestations of esophagitis, drugs are taken 1-2 capsules daily;
- It is advisable to use the medicine in the first half of the day. Taking medications Omez or Omeprazole is recommended immediately before meals with drinking plenty of water;
- The expected effect with a single use occurs 1 hour after use.
- The course of treatment is 14–28 days.
The instructions for any of the drugs in question include taking 1 capsule 3-4 hours before bedtime as a preventative measure for gastrointestinal diseases and to prevent acid aspiration.
If Helicobacter bacteria are detected in the body, Omez or Omeprazole is prescribed at a dosage of 20-40 mg in combination with amoxicillin (750 mg) twice a day for two weeks. However, for each specific case, the dosage and regimen may be changed, so in this case, consultation with a doctor is required.
If for some reason the next dose of the drug is missed, then you cannot take an increased dosage of Omez or Omeprazole at the same time.
"Omez" and "Omeprazole": the difference
In 1989, the Swedish pharmaceutical company Astra released the drug Losek. It became practically the first proton pump inhibitor drug. Despite its considerable price, the drug quickly sold out. Many pharmaceutical drug manufacturing companies have followed the well-trodden path and released their analogues - “Helol”, “Omeprazole”, “Omez”, “Omitox”, etc. Now these drugs are called the English term “generic”.
What is a generic? This name comes from English and is literally translated as “generic, generic.” This word refers to drugs that are analogues of patented drugs, the effect of which has already been proven and tested. The license for such drugs is valid for a limited time, and after its expiration, many pharmaceutical companies begin to produce their drugs under the most similar name with the addition/subtraction of letters or numbers. These are generics. Now there are many of them on the pharmaceutical market.
The common substance of the drugs is omeprazole. “Omez” and “Omeprazole” - the difference between these drugs is in price and additional auxiliary substances.
Thus, Omez is a generic version of Loseca, and Omeprazole is a generic version of Omeza.
What is the difference between Omez and Omeprazole? The first drug is produced in India, the second in Russia. “Omeprazole” represents the active substance in the maximum volume, while “Omez” is a drug that contains omeprazole and excipients that mitigate side effects and help the perception of the medicine.
Release form
Despite the difference between Omez and Omeprazole in the presence of additional components, the dosage of the main active ingredient in their composition is the same.
Omez capsules are hard, made of gelatin, with a transparent body and a pink cap. The capsule bears the inscription “OMEZ”. The contents of the capsules are white granular spherical powder containing the main active ingredient and auxiliary components.
Omeprazole capsules are hard capsules made of gelatin, with a white body and a red cap. Each capsule contains a granular spherical powder from white to light beige color, containing the main active ingredient and auxiliary components.
The dosages of the main active ingredient in these analogues are 10, 20 and 40 mg. Capsules are packaged in contour packaging of 10 pieces.
Reviews about "Omez"
What to choose – “Omez” or “Omeprazole”? Reviews will help you figure it out. “Omez” has been the flagship drug on the market for the treatment of gastritis for quite a long time. Unfortunately, many people have this disease, so medications are in demand. Based on an independent survey conducted on social networks among those taking the drug, we can come to the conclusion that it is effective. There is almost always a result. Another thing is side effects. The list is quite long, but if you have to take a drug that interferes with metabolism at a serious level, then you cannot do without side effects. As a remedy that helps restore the gastric mucosa, relieving symptoms and pain in gastrointestinal diseases, Omez has proven itself well among patients.
Therapeutic interchangeability: original drug or analogue
In fact, the first drug made on the basis of omeprazole and shown to work well in the treatment of stomach medications is Losek (Astra). This product first appeared on the pharmaceutical market in 1989. Due to its excellent clinical characteristics, other manufacturers began producing similar but cheaper generic drugs. Therefore, it is definitely quite difficult to say right away which is better than Omez or Omeprazole, since both of these drugs are analogues of the expensive Losek.
However, the price between the antiulcer analogue drugs themselves can also vary significantly. Since Omez is a product of the Indian pharmaceutical industry, it will accordingly be more expensive than Russian Omeprazole.
Reviews about Omeprazole
Not everyone knows about such a drug as Omeprazole. Patients often return from a gastroenterologist with a prescription for Omez. But you should not immediately accuse doctors of colluding with pharmaceutical components that are not in Omeprazole. According to the general reviews of the patients surveyed, the majority noted the effectiveness of the drug. But there are also complaints about side effects, such as:
- nausea;
- feeling of heaviness and discomfort;
- dry mouth and changes in taste;
- diarrhea or constipation.
Negative consequences in terms of general well-being were also noted:
- heaviness in the muscles;
- dizziness;
- insomnia or constant desire to sleep;
- depression;
- mood swings;
- changes in vision, negative non-negotiable processes are possible.
The drug is contraindicated during pregnancy and breastfeeding. In childhood, use is permissible only in the case of Zollinger-Ellison syndrome. It is worth saying that these side effects are also listed in the Omeza instructions, but in reality they are less common and less pronounced. This may be due to the higher degree of purification of the drug and its production processes.
When reception is undesirable
Regardless of whether Omez or Omeprazole is better, they, like many other medications, have their limitations. These drugs are not recommended for use if:
- individual intolerance to incoming substances;
- intestinal blockage or gastric obstruction;
- presence of brain tumors;
- hidden bleeding in the gastrointestinal tract;
- pregnancy and lactation.
Side effects of these drugs include the fact that long-term use may cause nausea, dizziness, headache, diarrhea or allergic manifestations. However, all these are quickly passing symptoms.
